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<docDscr>
  <citation>
    <titlStmt>
      <titl>Study of outcome trajectories and risk factors in a cohort of children and adolescents with Autism Spectrum Disorders (ASD)</titl>
      <IDNo>FRESH-PEF5021-en</IDNo>
    </titlStmt>
    <prodStmt>
      <producer abbr="" affiliation="CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER (CHU)" role="">Amaria BAGHDADLI</producer>
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<stdyDscr>
  <citation>
    <titlStmt>
      <titl>
                Study of outcome trajectories and risk factors in a cohort of children and adolescents with Autism Spectrum Disorders (ASD)            </titl>
      <altTitl>
                    ELENA-E0                </altTitl>
      <IDNo agency="FReSH-lang">
                FRESH-PEF5021-en            </IDNo>
      <IDNo agency="PEF">
                    5021                </IDNo>
      <IDNo agency="FReSH">
                    FRESH-PEF5021                </IDNo>
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    <rspStmt>
      <AuthEnty>
                    Amaria BAGHDADLI                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER (CHU)">
        <ExtLink title="ROR" URI="https://ror.org/00mthsf17" role="organisation id"/>
        <ExtLink title="SIREN" URI="263400160" role="organisation id"/>
      </AuthEnty>
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                                    </othId>
    </rspStmt>
    <prodStmt>
      <producer role="sponsor">
                                            CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER (CHU)                    
                                    </producer>
      <prodPlac>
                Epidemiology France Portal (PEF)            </prodPlac>
      <fundAg>
                                            CAISSE NATIONALE DE SOLIDARITE POUR L&amp;#039;AUTONOMIE (CNSA)                    
                                    </fundAg>
      <fundAg>
                                            CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER (CHU)                    
                                    </fundAg>
      <fundAg>
                                            MINISTERE DU TRAVAIL, DE LA SANTE, DES SOLIDARITES ET DES FAMILLES                    
                                    </fundAg>
    </prodStmt>
    <distStmt>
      <distrbtr abbr="null">
                    null</distrbtr>
      <contact affiliation="CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER (CHU)" email="dir2@impact-dev.tn">
                    Amaria;BAGHDADLI
                                            <ExtLink title="ROR" URI="https://ror.org/00mthsf17" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="263400160" role="organisation id"/>
                                    </contact>
      <depDate date="2026-05-26"/>
      <distDate date="2026-05-26"/>
    </distStmt>
    <biblCit format="">
            </biblCit>
    <holdings URI="null"/>
    <notes> </notes>
  </citation>
  <stdyInfo><studyBudget/><subject><keyword vocab="" vocabURI="">
                    trajectories of change</keyword><keyword vocab="" vocabURI="">
                    clinical epidemiology</keyword><keyword vocab="" vocabURI="">
                    childhood</keyword><keyword vocab="" vocabURI="">
                    adolescence</keyword><keyword vocab="" vocabURI="">
                    autism spectrum disorders</keyword><keyword vocab="" vocabURI="">
                    cohort</keyword><topcClas vocab="health theme">
                        Neurology                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/c4793dfe-e80e-49dd-9fcc-a1a742de1b25"/>
                                                            <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/00a5c4f4-b7ee-41a4-bcdf-3a02e6be1660"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D009462"/>
                                                </topcClas><topcClas vocab="health theme">
                        Paediatrics                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/bf8aaaac-ddee-41cd-bb8a-c5a63de3fcbd"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D010372"/>
                                                </topcClas><topcClas vocab="health theme">
                        Psychiatry                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/3de50dee-da1c-4791-a386-56bca24a5fed"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D011570"/>
                                                </topcClas><topcClas vocab="cim-11">
                        Neurodevelopmental disorders                                            </topcClas><topcClas vocab="health determinant">
                        Socio-demographic and economic determinants                    </topcClas><topcClas vocab="health determinant">
                        Biological determinants: Genetic predisposition                    </topcClas><topcClas vocab="health determinant">
                        Biological determinants                    </topcClas></subject>

        1) To describe the characteristics of a large sample of individuals with a diagnosis of ASD aged between 2 and 16 years, in the clinical, biological, developmental and psychosocial domains 2) To identify outcome trajectories over years and their determinants.<abstract contentType="purpose">null</abstract>        <abstract contentType="abstract">null</abstract>
        <sumDscr><collDate event="start" date="2012-01-01"/><nation abbr="fr">
                    France
                                            <concept vocab="ISO" vocabURI="fr"/>
                                    </nation><geogUnit/><anlyUnit>
                Individuals            </anlyUnit><universe level="type" clusion="I">Patients population                    </universe><universe level="sex" clusion="I">Male                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008297"/>
                                                    </universe><universe level="sex" clusion="I">Female                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D005260"/>
                                                    </universe><universe level="age" clusion="I">Child, Preschool (2 to 5 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D002675"/>
                                                    </universe><universe level="age" clusion="I">Child (6 to 12 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D002648"/>
                                                    </universe><universe clusion="I">Children and adolescents under age 20, with a diagnosis of ASD formally established by a multidisciplinary team according to international criteria. Parents must have given their oral consent.                    </universe><dataKind>Clinical data</dataKind><dataKind>Participant-reported health data</dataKind></sumDscr>
                
        



        

    </stdyInfo>
  <studyDevelopment>
    <developmentActivity type="primary evaluation">
      <description>Health event/morbidity
Health event/mortality
Health care consumption and services
Quality of life/health perception</description>
    </developmentActivity>
  </studyDevelopment>
  <method>
    <dataColl>
      <sampProc>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </sampProc>
      <sampleFrame>
        <frameUnit>
          <unitType>Through organizations (health services or institutions</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>schools</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>businesses</unitType>
        </frameUnit>
        <frameUnit>
          <unitType>etc.)</unitType>
        </frameUnit>
      </sampleFrame>
      <targetSampleSize>
        <sampleSizeFormula>[500-1000[ individuals                        </sampleSizeFormula>
      </targetSampleSize>
      <collMode>Interview with the participant (including clinical)                                                            <concept vocab="CESSDA" vocabURI="Interview"/>
                                                    </collMode>
    </dataColl>
    <notes>Observational Study</notes>
    <notes subject="research type">
                        Observational Study                    </notes>
    <notes subject="observational study method">
                        Cohort study                    </notes>
    <anlyInfo>
      <respRate>550 patients recruted</respRate>
    </anlyInfo>
    <stdyClas>Unknown</stdyClas>
  </method>
  <dataAccs>
    <setAvail>
      <avlStatus>
                            Restricted access                                                    </avlStatus>
    </setAvail>
    <useStmt>
      <conditions>access to the data base is subject to the approval of the scientific leader and the sponsor of the study</conditions>
    </useStmt>
  </dataAccs>
  <othrStdyMat>
    <relMat>Access on specific project only</relMat>
  </othrStdyMat>
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<dataDscr>
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