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<docDscr>
  <citation>
    <titlStmt>
      <titl>National register of des pediatric hematological malignancies</titl>
      <IDNo>FRESH-PEF61-en</IDNo>
    </titlStmt>
    <prodStmt>
      <producer abbr="" affiliation="INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)" role="">Jacqueline CLAVEL</producer>
    </prodStmt>
    <verStmt>
      <version></version>
    </verStmt>
  </citation>
</docDscr>
<stdyDscr>
  <citation>
    <titlStmt>
      <titl>
                National register of des pediatric hematological malignancies            </titl>
      <altTitl>
                    RNHE                </altTitl>
      <IDNo agency="FReSH-lang">
                FRESH-PEF61-en            </IDNo>
      <IDNo agency="PEF">
                    61                </IDNo>
      <IDNo agency="FReSH">
                    FRESH-PEF61                </IDNo>
    </titlStmt>
    <rspStmt>
      <AuthEnty>
                    Jacqueline CLAVEL                                                                                                                            </AuthEnty>
      <AuthEnty affiliation="INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)">
        <ExtLink title="ROR" URI="https://ror.org/02vjkv261" role="organisation id"/>
        <ExtLink title="SIREN" URI="180036048" role="organisation id"/>
      </AuthEnty>
      <othId affiliation="" type="">
                                    </othId>
      <othId affiliation="" type="">
                                    </othId>
    </rspStmt>
    <prodStmt>
      <producer role="sponsor">
                                            INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)                    
                                    </producer>
      <prodPlac>
                Epidemiology France Portal (PEF)            </prodPlac>
      <fundAg>
                                            INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)                    
                                    </fundAg>
      <fundAg>
                                            INSTITUT NATIONAL DU CANCER (INCA)                    
                                    </fundAg>
      <fundAg>
                                            SANTE PUBLIQUE FRANCE                    
                                    </fundAg>
    </prodStmt>
    <distStmt>
      <distrbtr abbr="null">
                    null</distrbtr>
      <contact affiliation="INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)" email="dir5@impact-dev.tn">
                    Jacqueline;CLAVEL
                                            <ExtLink title="ROR" URI="https://ror.org/02vjkv261" role="organisation id"/>
                                            <ExtLink title="SIREN" URI="180036048" role="organisation id"/>
                                    </contact>
      <depDate date="2026-05-26"/>
      <distDate date="2026-05-26"/>
    </distStmt>
    <biblCit format="">
            </biblCit>
    <holdings URI="null"/>
    <notes> </notes>
  </citation>
  <stdyInfo><studyBudget/><subject><keyword vocab="" vocabURI="">
                    incidence rates</keyword><keyword vocab="" vocabURI="">
                    types of leukemia and lymphoma</keyword><keyword vocab="" vocabURI="">
                    particular exposure</keyword><keyword vocab="" vocabURI="">
                    HIV mother</keyword><keyword vocab="" vocabURI="">
                    perinatal period</keyword><keyword vocab="" vocabURI="">
                    environmental exposures</keyword><keyword vocab="" vocabURI="">
                    survival</keyword><keyword vocab="" vocabURI="">
                    general population</keyword><keyword vocab="" vocabURI="">
                    risk</keyword><topcClas vocab="health theme">
                        Oncology                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/5784b7f1-c7ce-49d9-9f38-aebcda0ff41d"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D008495"/>
                                                </topcClas><topcClas vocab="health theme">
                        Hematology                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/9239f328-78c9-40a5-a0b9-8e66fd9b6245"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D006402"/>
                                                </topcClas><topcClas vocab="health theme">
                        Paediatrics                                                        <ExtLink title="ESV" URI="http://data.europa.eu/8mn/euroscivoc/bf8aaaac-ddee-41cd-bb8a-c5a63de3fcbd"/>
                                                            <ExtLink title="MeSH" URI="http://id.nlm.nih.gov/mesh/D010372"/>
                                                </topcClas><topcClas vocab="cim-11">
                        Neoplasms                                            </topcClas><topcClas vocab="health determinant">
                        Biological determinants: Genetic predisposition                    </topcClas><topcClas vocab="health determinant">
                        Environmental determinants: Other                    </topcClas><topcClas vocab="health determinant">
                        Behavioral determinants                    </topcClas><topcClas vocab="health determinant">
                        Environmental determinants                    </topcClas><topcClas vocab="health determinant">
                        Biological determinants                    </topcClas></subject>

        1) Establish low incidence rates for the various types of leukemia and lymphoma. 2) Provide continuous follow-up of the incidence and detect any increase in the national or localized incidence. 3) Supply the estimation of the survival in the general population of the various types of leukemia and lymphoma. 4) Contribute to following-up on the risk of pediatric cancers in populations subjected to particular exposure (children who have had a scan, child of an HIV mother and treated during the perinatal period, environmental exposures). 5) Provide the data that will make it possible to evaluate the care sectors for children from the first symptoms until treatment. 6) Contribute to the work in research on the risks factors of cancer in children developed by the team on Environmental epidemiology of cancers of the CESP, INSERM U1018.<abstract contentType="purpose">null</abstract>        <abstract contentType="abstract">null</abstract>
        <sumDscr><collDate event="start" date="1990-01-01"/><nation abbr="fr">
                    France
                                            <concept vocab="ISO" vocabURI="fr"/>
                                    </nation><geogUnit/><anlyUnit>
                Individuals            </anlyUnit><universe level="type" clusion="I">Patients population                    </universe><universe level="sex" clusion="I">Male                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D008297"/>
                                                    </universe><universe level="sex" clusion="I">Female                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D005260"/>
                                                    </universe><universe level="age" clusion="I">Infant, Newborn (birth to 28 days)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D007231"/>
                                                    </universe><universe level="age" clusion="I">Infant (28 days to 2 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D007223"/>
                                                    </universe><universe level="age" clusion="I">Child, Preschool (2 to 5 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D002675"/>
                                                    </universe><universe level="age" clusion="I">Child (6 to 12 years)                                                            <concept vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D002648"/>
                                                    </universe><universe clusion="I">Population less than 18 years of age suffering from primitive or secondary hematological or borderline malignancy (leukemia, lymphoma, myelodysplastic syndrome, myeloproliferative disease, Langerhans cell histiocytosis).                    </universe><dataKind>Clinical data</dataKind><dataKind>Biological data</dataKind><dataKind>Socio-demographic data</dataKind><dataKind>Paraclinical data (non-biological) : Imaging</dataKind></sumDscr>
                
        



        

    </stdyInfo>
  <studyDevelopment>
    <developmentActivity type="primary evaluation">
      <description>Health event/morbidity
Health event/mortality
Health care consumption and services</description>
    </developmentActivity>
  </studyDevelopment>
  <method>
    <dataColl>
      <sampProc>Other                                                            <concept vocab="CESSDA" vocabURI="Other"/>
                                                    </sampProc>
      <targetSampleSize>
        <sampleSizeFormula>[10000-20000[ individuals                        </sampleSizeFormula>
      </targetSampleSize>
      <collMode>Physical/biological measurements (blood pressure, weight, biochemistry, imaging, etc.)                                                            <concept vocab="CESSDA" vocabURI="MeasurementsAndTests.Physical"/>
                                                    </collMode>
      <collMode>Converting or copying information into a structured record                                                            <concept vocab="CESSDA" vocabURI="Transcription"/>
                                                    </collMode>
      <sources>
        <sources>
          <sourceCitation>
                                    
                                    
                                                                    </sourceCitation>
          <srcOrig>Medico-administrative database</srcOrig>
        </sources>
      </sources>
    </dataColl>
    <notes>Observational Study</notes>
    <notes subject="research type">
                        Observational Study                    </notes>
    <notes subject="observational study method">
                        Morbidity registry                    </notes>
    <anlyInfo>
      <respRate>6640</respRate>
    </anlyInfo>
    <stdyClas>Unknown</stdyClas>
  </method>
  <dataAccs>
    <setAvail>
      <avlStatus>
                            Restricted access                                                    </avlStatus>
    </setAvail>
  </dataAccs>
  <othrStdyMat>
    <relMat>Access on specific project only</relMat>
  </othrStdyMat>
</stdyDscr>
<dataDscr>
</dataDscr></codeBook>
